Maximise the potential of your stem cell applications

Meet Sistemic experts at Stem Cell Meeting on the MESA

29 November: Sistemic, UK: Dr Verna McErlane, Director of Commercial Operations, International at Sistemic, is scheduled to give her own special insight into advanced analytical models to support the stem cell therapy industry at this year’s Stem Cell Meeting on the MESA conference. Participants will have the opportunity to discuss miRNA profiling and learn how to maximise the potential of stem cell applications. The 2011 conference will be held in the Salk Institute for Biological Studies in La Jolla, California on November 30 and December 1. 

Acknowledged experts in cell characterization, Sistemic has recognized a need in the stem cell industry for improved miRNA profiling methodology. The company’s unique approach to miRNA analysis presents significant benefits to stem cell research by providing the tools needed for accurate and rapid cell characterization and an excellent platform for validation prior to commercialization.

Dr Verna McErlane said: “As members of the Alliance for Regenerative Medicine, who are co-organisers of this event, we are particularly delighted to be attending this meeting, which we believe is the premier event for those involved in the stem cell industry.”

 Stem Cell Meeting on the MESA is a two-day conference, which is aimed at bringing together the scientific research and business communities. Dr McErlane will be available throughout the two days to discuss your stem cell analysis objectives and how Sistemic can help you meet those objectives more easily. Sistemic looks forward to meeting you there and supporting the event organizers in their goal to facilitate a bridge between academia and industry and further the translation of clinical research.

For further information come along to the meeting or contact Sistemic directly www.sistemic.co.uk

Sistemic presents the solution for broader stem cell therapy at AUSBiotech 2011

18 October : Sistemic, UK:  Verna McErlane, Director of Commercial Operations for miRNA specialist Sistemic, is attending AUSBiotech 2011 in Adelaide, South Australia, 16-19 October. At this event she presented a talk entitled ‘The Challenges of Advancing Stem Cell Therapies into the clinic; a Characterisation Perspective’. The presentation formed part of the ‘Human Health – Clever cell culture for the innovation of biologics’ session on 18 October.

Dr McErlane’s talk provided an intuitive overview of the cell therapy market including future promise, what has been achieved to date, followed by a review of some of the challenges in bringing a cell therapy to the clinic. She then focused on cell characterisation and the utility of using miRNA fingerprinting by showcasing recent case studies where Sistemic SistemQC technology has provided unique insight to assist stem cell developers produce better and more standardised cells.

“The stem cell sector has already shown its promise in producing effective treatments but these are just the tip of the iceberg and there is the potential for so much more,” said Dr McErlane. “The cell therapy industry is at a critical cross-roads during its evolution into the clinical environment and there are some real challenges ahead including a definite need for reliable standardisation and characterisation methodology.”

Jim Reid, CEO of Sistemic commented, “At Sistemic we are addressing key challenges and, in conjunction with our stem cell clients, coming up with practical solutions which will enhance the potential of these developments in safe and effective patient treatment.”

The translation of stem cell technology from the lab into the clinic requires reliable monitoring and characterisation methodology. Sistemics’ SistemRNA and SistemQC use a stem cell focused, miRNA-based approach which molecularly characterises cells and monitors their quality. Not only does it give a succinct read out on the status of the cells, but also provides an insight into the underlying biological effects associated with any change observed. This is being used by the stem cell community to optimise and guide the differentiation process, benchmark differentiated cells and, from a manufacturing perspective, provide identity markers, purity and potency control. Such innovative developments, together with other new tools and a consensus on the stardardisation process, are what will really drive this industry forward to reach its full potential.

 Sistemic looks forward to meeting old colleagues, new faces and learning about the most recent developments in the field at AUSBiotech 2011 . Visitors can meet the team at the Scottish Development International booth in the exhibition hall. In the meantime, anyone interested in Sistemic and its products should visit: www.sistemic.co.uk

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Sistemic highlights the need for better cell characterisation in regenerative medicine

03 October 2011: Sistemic, UK:  Sistemic, the cell characterisation problem-solving service provider that uses miRNA, is a strong advocate for the potential of regenerative medicine. Dr Verna McErlane, Sistemic’s Director of Commercial Operations, recently took part in a round-table discussion with leading stem cell researchers http://www.sistemic.co.uk/publications. The scientific, ethical and moral debate about the use of stem cells continues and will soon be taken up in earnest at the World Stem Cell Summit, taking place from 3-5 October in Pasadena, California, where Dr McErlane is a key participant.

 “The future for regenerative medicine is huge, but there are issues to be faced on this road to success,” said Dr McErlane. “Firstly we need to establish reliable cell standards, and secondly these standards should inform the development of a validated and dependable toolbox for monitoring and characterising stem cells during research and manufacturing. Only through characterisation can this technology enter the mainstream clinical practice and provide the patient benefits we are all hoping for.”

 Sistemic has developed a stem cell focused miRNA-based approach called SistemQC™ which molecularly characterises cells and monitors their quality. Not only does it give a succinct read out on the status of the cells but also provides an insight into the underlying biological effects associated with any change observed. SistemQC™ is being used by the stem cell community to optimise and guide the differentiation process, benchmark differentiated cells and, from a manufacturing perspective, provide identity markers, purity and potency control. Innovative developments such as this, as well as other new tools and a consensus on the standardisation of the process, are that will really drive this industry forward to reach its full potential.

 Dr McErlane went on to say, “Without adequate control, this unique opportunity to positively impact on the treatment of many untreatable conditions will be lost. Standardisation is key and Sistemic are at the forefront of assisting in making Regenerative Medicine a reality for clinical practice.”

 Initiated in 2009, the World Stem Cell Summit (http://www.worldstemcellsummit.com/) has quickly become one of the largest interdisciplinary, networking meetings of stem cell stakeholders, which unites the regenerative medicine industry and biomedical research. For 2011, one of the industry key note addresses, given by Dr Gil Van Bokkelen co-founder and CEO of Athersys and Chairman of the Alliance for Regenerative Medicine, of which Sistemic is a key member , will be; ‘The transformational potential of regenerative medicine, and how it will change healthcare as we know it’.

 Sistemic looks forward to meeting old colleagues, new faces and learning about the most recent developments in the field at the upcoming World Stem Cell Summit. Visitors can meet the team at the Scottish Development International Booth in the exhibit hall. In the meantime, anyone interested in Sistemic and its products should visit: www.sistemic.co.uk

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